LIG3 antibody (AA 809-928)

Catalog No. ABIN7150193

Product Details anti-LIG3 Antibody

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Binding Specificity: AA 809-928

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIG3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA ligase 3 protein (809-928AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Alternative Name: LIG3 (LIG3 Products)

Synonyms: orf36 antibody, DDBDRAFT_0218523 antibody, DDBDRAFT_0232266 antibody, DDB_0218523 antibody, DDB_0232266 antibody, LIG3 antibody, wu:fb12c02 antibody, wu:fd10b03 antibody, wu:fm79b09 antibody, LIG2 antibody, D11Wsu78e antibody, An02g06890 antibody, AO090003000668 antibody, lig3 antibody, DNA ligase III antibody, BRCT domain-containing protein antibody, DNA ligase 3 antibody, ligase III, DNA, ATP-dependent antibody, ligase III, DNA, ATP-dependent L homeolog antibody, orf36 antibody, lig3 antibody, LIG3 antibody, Lig3 antibody, Bm1_22840 antibody, ANI_1_2644024 antibody, AOR_1_1174154 antibody, LOC100634887 antibody, lig3.L antibody

Background:

Background: Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).

Aliases: D11Wsu78e antibody, DNA ligase antibody, DNA ligase 3 antibody, DNA ligase III antibody, DNLI3_HUMAN antibody, LIG 3 antibody, LIG2 antibody, LIG3 antibody, Ligase II, DNA, ATP dependent antibody, Ligase III DNA ATP dependent antibody, MGC78176 antibody, OTTMUSP00000000875 antibody, Polydeoxyribonucleotide synthase [ATP] 3 antibody, Polydeoxyribonucleotide synthase [ATP] antibody, Polydeoxyribonucleotide synthase antibody, RP23-316C11.6 antibody

UniProt: P49916

Pathways: DNA Damage Repair