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DIS3L2 antibody (AA 201-400)

DIS3L2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7150017
  • Target See all DIS3L2 Antibodies
    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
    Binding Specificity
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-400
    Reactivity
    • 36
    • 20
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    • 9
    • 1
    Rabbit
    Clonality
    • 29
    • 8
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DIS3L2 antibody is un-conjugated
    Application
    • 26
    • 13
    • 6
    • 6
    • 5
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human DIS3-like exonuclease 2 protein (201-400AA)
    Isotype
    IgG
    Top Product
    Discover our top product DIS3L2 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
    Alternative Name
    DIS3L2 (DIS3L2 Products)
    Synonyms
    RGD1560168 antibody, DIS3L2 antibody, DKFZp469O0522 antibody, FAM6A antibody, PRLMNS antibody, hDIS3L2 antibody, 4930429A22Rik antibody, 8030493P09Rik antibody, DIS3-like 3'-5' exoribonuclease 2 antibody, DIS3 like 3'-5' exoribonuclease 2 antibody, DIS3-like exonuclease 2 antibody, Dis3l2 antibody, DIS3L2 antibody, LOC100344728 antibody
    Background

    Background: 3\'-5\'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3\' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3\'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.

    Aliases: DI3L2_HUMAN antibody, DIS3 L2 antibody, DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody, DIS3 mitotic control homolog like 2 antibody, DIS3-like exonuclease 2 antibody, Dis3l2 antibody, FLJ36974 antibody, MGC42174 antibody

    UniProt
    Q8IYB7
    Pathways
    Stem Cell Maintenance
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