Diphthamide Biosynthesis 7 (DPH7) (AA 210-325) antibody

Catalog No. ABIN7150005

Product Details

Target: Diphthamide Biosynthesis 7 (DPH7)

Binding Specificity: AA 210-325

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Diphthine methyltransferase protein (210-325AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Diphthamide Biosynthesis 7 (DPH7)

Alternative Name: DPH7 (DPH7 Products)

Synonyms: C9orf112 antibody, RP11-48C7.3 antibody, RRT2 antibody, WDR85 antibody, diphthamide biosynthesis 7 antibody, DPH7 antibody

Background:

Background: Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).

Aliases: C9orf112 antibody, Diphthamide biosynthesis 7 antibody, DPH7 antibody, FLJ90634 antibody, OTTHUMP00000022705 antibody, RP11-48C7.3 antibody, RRT2 antibody, WD repeat domain 85 antibody, WD repeat-containing protein 85 antibody, wdr85 antibody, WDR85_HUMAN antibody

UniProt: Q9BTV6