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DKK2 antibody (AA 34-259)

DKK2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7149882
  • Target See all DKK2 Antibodies
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Binding Specificity
    • 9
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 34-259
    Reactivity
    • 55
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 50
    • 4
    • 1
    Rabbit
    Clonality
    • 51
    • 4
    Polyclonal
    Conjugate
    • 27
    • 8
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DKK2 antibody is un-conjugated
    Application
    • 43
    • 28
    • 26
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Dickkopf-related protein 2 protein (34-259AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    DKK2 (Dickkopf 2 Homolog (DKK2))
    Alternative Name
    DKK2 (DKK2 Products)
    Synonyms
    DKK-2 antibody, Dkk4 antibody, zgc:171574 antibody, dickkopf WNT signaling pathway inhibitor 2 antibody, DKK2 antibody, Dkk2 antibody, dkk2 antibody
    Background

    Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

    Aliases: Dickkopf 2 antibody, Dickkopf gene 2 antibody, Dickkopf homolog 2 antibody, Dickkopf related protein 2 antibody, Dickkopf WNT signaling pathway inhibitor 2 antibody, Dickkopf-2 antibody, Dickkopf-related protein 2 antibody, Dickkopf2 antibody, DKK 2 antibody, Dkk-2 antibody, Dkk2 antibody, DKK2_HUMAN antibody, hDkk 2 antibody, hDkk-2 antibody, hDkk2 antibody

    UniProt
    Q9UBU2
    Pathways
    WNT Signaling
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