Transmembrane 7 Superfamily Member 4 (TM7SF4) (AA 119-209) antibody (HRP)

Catalog No. ABIN7149666

Product Details

Target: Transmembrane 7 Superfamily Member 4 (TM7SF4)

Binding Specificity: AA 119-209

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Dendritic cell-specific transmembrane protein (119-209AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Transmembrane 7 Superfamily Member 4 (TM7SF4)

Alternative Name: DCSTAMP (TM7SF4 Products)

Synonyms: Tm7sf4 antibody, TM7SF4 antibody, FIND antibody, hDC-STAMP antibody, 4833414I07Rik antibody, DC-STAMP antibody, mDC-STAMP antibody, dendrocyte expressed seven transmembrane protein antibody, Dcstamp antibody, DCSTAMP antibody

Background:

Background: Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.

Aliases: DC-STAMP antibody, DCSTAMP antibody, DCSTP_HUMAN antibody, Dendritic cell-specific transmembrane protein antibody, Dendrocyte-expressed seven transmembrane protein antibody, FIND antibody, hDC-STAMP antibody, IL-Four INDuced antibody, IL-four-induced protein antibody, Transmembrane 7 superfamily member 4 antibody

UniProt: Q9H295