DLL4 antibody (AA 44-345)

Catalog No. ABIN7149653

Product Details anti-DLL4 Antibody

Target: DLL4 (delta-Like 4 (DLL4))

Binding Specificity: AA 44-345

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Delta-like protein 4 protein (44-345AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4 (DLL4 Products)

Synonyms: hdelta2 antibody, Delta4 antibody, si:ch211-244p18.5 antibody, zgc:136596 antibody, delta like canonical Notch ligand 4 antibody, delta-like 4 (Drosophila) antibody, DLL4 antibody, Dll4 antibody, dll4 antibody

Background:

Background: Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344).

Aliases: AOS6 antibody, Delta 4 antibody, delta 4 precursor antibody, Delta ligand 4 antibody, delta ligand 4 precursor antibody, Delta like 4 antibody, Delta like 4 homolog antibody, Delta like 4 protein antibody, Delta like canonical Notch ligand 4 antibody, Delta like protein 4 antibody, Delta-like 4 (Drosophila) antibody, Delta-like protein 4 antibody, Delta4 antibody, DLL 4 antibody, Dll4 antibody, DLL4_HUMAN antibody, Drosophila Delta homolog 4 antibody, hdelta2 antibody, Homeobox protein DLL-4 antibody, MGC126344 antibody, Notch ligand delta 2 antibody, Notch ligand DLL4 antibody, Notch ligand DLL4 precursor antibody, XDLL-4 antibody

UniProt: Q9NR61

Pathways: Notch Signaling