DOCK7 antibody (AA 1440-1671)
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- Target See all DOCK7 Antibodies
- DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
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Binding Specificity
- AA 1440-1671
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DOCK7 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
- Isotype
- IgG
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anti-Dedicator of Cytokinesis 7 (DOCK7) (N-Term) antibody
DOCK7 Reactivity: Human, Rat, Mouse ELISA, WB Host: Rabbit Polyclonal unconjugated
anti-Dedicator of Cytokinesis 7 (DOCK7) (AA 1-624) antibodyDOCK7 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:2000-1:5000, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
- Alternative Name
- DOCK7 (DOCK7 Products)
- Synonyms
- im:7145816 antibody, im:7157388 antibody, wu:fb93h07 antibody, ZIR2 antibody, 3110056M06Rik antibody, Gm430 antibody, m antibody, mKIAA1771 antibody, dedicator of cytokinesis 7 antibody, dedicator of cytokinesis protein 7 antibody, dedicator of cytokinesis 6 antibody, DOCK7 antibody, dock7 antibody, NAEGRDRAFT_56982 antibody, LOC100185115 antibody, dock6 antibody, Dock7 antibody
- Background
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Background: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 \\\'Ser-15\\\' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).
Aliases: DOCK7 antibody, KIAA1771Dedicator of cytokinesis protein 7 antibody
- UniProt
- Q96N67
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