DOM3Z antibody (AA 69-266) (HRP)

Catalog No. ABIN7149570

Product Details anti-DOM3Z Antibody (HRP)

Target: DOM3Z (Dom-3 Homolog Z (DOM3Z))

Binding Specificity: AA 69-266

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOM3Z antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Decapping and exoribonuclease protein (69-266AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DOM3Z

Target: DOM3Z (Dom-3 Homolog Z (DOM3Z))

Alternative Name: DXO (DOM3Z Products)

Synonyms: ng6 antibody, dom3l antibody, DXO antibody, DOM3L antibody, NG6 antibody, RAI1 antibody, decapping exoribonuclease antibody, dom-3 homolog Z (C. elegans) antibody, decapping exoribonuclease L homeolog antibody, DXO antibody, DOM3Z antibody, dxo antibody, dxo.L antibody, Dxo antibody

Background:

Background: Ribonuclease that specifically degrades pre-mRNAs with a defective 5\' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5\'-3\' exonuclease activities. Has decapping activity toward incomplete 5\' end cap mRNAs such as unmethylated 5\' end-capped RNA to release GpppN and 5\' end monophosphate RNA. The 5\' end monophosphate RNA is then degraded by the 5\'-3\' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5\'-pyrophosphohydrolase activity by hydrolyzing the 5\' end triphosphate to release pyrophosphates (By similarity).

Aliases: Dom 3 homolog Z antibody, DOM 3Z antibody, Dom-3 homolog Z antibody, DOM3 C. elegans homolog of Z antibody, Dom3 homolog Z antibody, DOM3L antibody, Dom3z antibody, DOM3Z_HUMAN antibody, NG6 antibody, Protein Dom3Z antibody, RAI1 antibody, RAT1-INTERACTING PROTEIN 1 antibody

UniProt: O77932