DAPK2 antibody (AA 222-370)

Catalog No. ABIN7149554

Product Details anti-DAPK2 Antibody

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Binding Specificity: AA 222-370

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAPK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Death-associated protein kinase 2 protein (222-370AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DAPK2

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Alternative Name: DAPK2 (DAPK2 Products)

Synonyms: drp1 antibody, drp-1 antibody, DAPK2 antibody, dapk2 antibody, DRP-1 antibody, DRP1 antibody, death-associated protein kinase 2 L homeolog antibody, death associated protein kinase 2 antibody, death-associated protein kinase 2b antibody, death-associated protein kinase 2 antibody, dapk2.L antibody, DAPK2 antibody, dapk2b antibody, dapk2 antibody, Dapk2 antibody

Background:

Background: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.

Aliases: DAK2 antibody, DAP kinase 2 antibody, DAP kinase related protein 1 antibody, DAP kinase related protein 1 beta isoform antibody, DAP-kinase-related protein 1 antibody, DAPK2 antibody, DAPK2_HUMAN antibody, Death associated protein kinase 2 antibody, Death-associated protein kinase 2 antibody, DRP 1 antibody, DRP-1 antibody, DRP1 antibody, MGC119312 antibody

UniProt: Q9UIK4