Aconitase 1 antibody (AA 508-745)
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- Target See all Aconitase 1 (ACO1) Antibodies
- Aconitase 1 (ACO1)
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Binding Specificity
- AA 508-745
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Aconitase 1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Cytoplasmic aconitate hydratase protein (508-745AA)
- Isotype
- IgG
- Top Product
- Discover our top product ACO1 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Aconitase 1 (ACO1)
- Alternative Name
- ACO1 (ACO1 Products)
- Synonyms
- ACONS antibody, IREB1 antibody, IREBP antibody, IREBP1 antibody, IRP1 antibody, Acon1 antibody, Ratireb antibody, ratireb antibody, Aco1 antibody, AI256519 antibody, Aco-1 antibody, Irebp antibody, Irp1 antibody, aconitase 1 antibody, aconitase 1, soluble antibody, aconitase 1 L homeolog antibody, ACO1 antibody, Aco1 antibody, aco1.L antibody
- Background
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Background: Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
Aliases: ACO 1 antibody, ACO1 antibody, ACOC_HUMAN antibody, Aconitase 1 soluble antibody, Aconitase antibody, Aconitase1 antibody, Aconitate hydratase antibody, ACONS antibody, Citrate hydro lyase antibody, Citrate hydro-lyase antibody, Cytoplasmic aconitate hydratase antibody, Ferritin repressor protein antibody, IRE BP 1 antibody, IRE-BP 1 antibody, IREB 1 antibody, IREB1 antibody, IREBP antibody, IREBP1 antibody, Iron regulatory protein 1 antibody, Iron responsive element binding protein 1 antibody, Iron-responsive element-binding protein 1 antibody, IRP 1 antibody, IRP1 antibody, OTTHUMP00000045233 antibody
- UniProt
- P21399
- Pathways
- Transition Metal Ion Homeostasis
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