UQCRFS1 antibody (AA 79-274)

Catalog No. ABIN7149114

Product Details anti-UQCRFS1 Antibody

Target: UQCRFS1 (Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 (UQCRFS1))

Binding Specificity: AA 79-274

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UQCRFS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cytochrome b-c1 complex subunit Rieske, mitochondrial protein (79-274AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UQCRFS1

Target: UQCRFS1 (Ubiquinol-Cytochrome C Reductase, Rieske Iron-Sulfur Polypeptide 1 (UQCRFS1))

Alternative Name: UQCRFS1 (UQCRFS1 Products)

Synonyms: uqcrfs1 antibody, MGC53134 antibody, rip1 antibody, ris1 antibody, risp antibody, uqcr5 antibody, fb78f10 antibody, wu:fb05d11 antibody, wu:fb78f10 antibody, wu:fj05e12 antibody, zgc:73109 antibody, zgc:85614 antibody, GLEAN_00043 antibody, RIP1 antibody, RIS1 antibody, RISP antibody, UQCR5 antibody, 4430402G14Rik antibody, AI875505 antibody, LRRGT00195 antibody, UQCRFSL1 antibody, ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 S homeolog antibody, ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 antibody, cytochrome b-c1 complex subunit Rieske, mitochondrial antibody, iron-sulfur protein 1 antibody, uqcrfs1.S antibody, uqcrfs1 antibody, LOC661125 antibody, LOC705178 antibody, UQCRFS1 antibody, Uqcrfs1 antibody, LOC100227575 antibody, isp1 antibody

Background:

Background: Cytochrome b-c1 complex subunit Rieske, mitochondrial: Component of the mitochondrial ubiquinol-cytochrome c reductase complex dimer (complex III dimer), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (PubMed:28673544). Incorporation of UQCRFS1 is the penultimate step in complex III assembly (PubMed:28673544). Cytochrome b-c1 complex subunit 9: Possible component of the mitochondrial ubiquinol-cytochrome c reductase complex dimer (complex III dimer), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (PubMed:28673544). UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer, including this fragment, called subunit 9, which corresponds to the transit peptide (PubMed:28673544). The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function (PubMed:28673544). It is therefore unsure whether the UQCRFS1 fragments, including this fragment, are structural subunits (PubMed:28673544).

Aliases: Complex III subunit 5 antibody, Complex III subunit IX antibody, Cytochrome b c1 complex subunit Rieske mitochondrial antibody, Cytochrome b-c1 complex subunit 11 antibody, Cytochrome b-c1 complex subunit 5 antibody, Cytochrome b6f complex iron sulfur subunit, chloroplastic antibody, petC antibody, PGR1 antibody, Plastohydroquinone:plastocyanin oxidoreductase iron sulfur protein antibody, Proton gradient regulation protein 1 antibody, Rieske iron sulfur protein antibody, Rieske iron-sulfur protein antibody, RIP1 antibody, RIS1 antibody, RISP antibody, Ubiquinol cytochrome C reductase rieske iron sulphur antibody, Ubiquinol cytochrome c reductase Rieske iron-sulfur polypeptide 1 antibody, Ubiquinol-cytochrome c reductase 8 kDa protein antibody, Ubiquinol-cytochrome c reductase iron-sulfur subunit antibody, UCRI_HUMAN antibody, UQCR5 antibody, UQCRFS1 antibody

UniProt: P47985

Pathways: Proton Transport