ATG4D antibody (AA 14-43)

Catalog No. ABIN7149030

Product Details anti-ATG4D Antibody

Target: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Binding Specificity: AA 14-43

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4D antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cysteine protease ATG4D protein (14-43AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATG4D

Target: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Alternative Name: ATG4D (ATG4D Products)

Synonyms: APG4-D antibody, APG4D antibody, AUTL4 antibody, 9830134P12Rik antibody, Apg4d antibody, Atg4dl antibody, Autl4 antibody, apg4d antibody, autophagy related 4D cysteine peptidase antibody, autophagy related 4D, cysteine peptidase antibody, autophagy related 4D, cysteine peptidase L homeolog antibody, ATG4D antibody, Atg4d antibody, atg4d.L antibody

Background:

Background: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Aliases: 9830134P12Rik antibody, APG4 autophagy 4 homolog D antibody, APG4 D antibody, APG4, S. cerevisiae, homolog of, D antibody, APG4D antibody, ATG4 autophagy related 4 homolog D (S. cerevisiae) antibody, Atg4d antibody, ATG4D_HUMAN antibody, Atg4dl antibody, AUT like 4 cysteine endopeptidase antibody, AUT-like 4 cysteine endopeptidase antibody, AUTL4 antibody, Autophagin 4 antibody, Autophagin-4 antibody, autophagy 4, S. cerevisiae, homolog of, D antibody, autophagy related 4D, cysteine peptidase antibody, Autophagy related cysteine endopeptidase 4 antibody, Autophagy related protein 4 homolog D antibody, Autophagy-related cysteine endopeptidase 4 antibody, Autophagy-related protein 4 homolog D antibody, Cysteine protease ATG4D antibody, Cysteine protease involved in autophagy antibody, MGC31226 antibody

UniProt: Q86TL0

Pathways: Autophagy