ATG4B antibody (AA 350-400)

Catalog No. ABIN7149021

Product Details anti-ATG4B Antibody

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Binding Specificity: AA 350-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cysteine protease ATG4B protein (350-400AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Alternative Name: ATG4B (ATG4B Products)

Synonyms: apg4b antibody, APG4B antibody, AUTL1 antibody, 2510009N07Rik antibody, AW048066 antibody, Apg4b antibody, Atg4bl antibody, Autl1 antibody, Aut2b2 antibody, autophagy related 4B cysteine peptidase antibody, autophagy-related 4b antibody, Peptidase family C54 protein antibody, cysteine protease ATG4B antibody, ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody, autophagy related 4B, cysteine peptidase antibody, autophagy related 4B, cysteine peptidase L homeolog antibody, ATG4B antibody, Atg4b antibody, AT3G59950 antibody, Tsp_08582 antibody, Tsp_11599 antibody, atg4b antibody, atg4b.L antibody

Background:

Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Aliases: APG4 autophagy 4 homolog B antibody, APG4B antibody, ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody, ATG4B antibody, ATG4B_HUMAN antibody, AUT like 1 cysteine endopeptidase antibody, AUT-like 1 cysteine endopeptidase antibody, AUTL1 antibody, Autophagin 1 antibody, Autophagin-1 antibody, Autophagy related 4B cysteine peptidase antibody, Autophagy related cysteine endopeptidase 1 antibody, Autophagy related protein 4 homolog B antibody, Autophagy-related cysteine endopeptidase 1 antibody, Autophagy-related protein 4 homolog B antibody, Cysteine protease ATG4B antibody, hAPG4B antibody, MGC1353 antibody

UniProt: Q9Y4P1

Pathways: Autophagy