CDK3 antibody (AA 220-297) (Biotin)
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- Target See all CDK3 Antibodies
- CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
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Binding Specificity
- AA 220-297
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDK3 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Cyclin-dependent kinase 3 protein (220-297AA)
- Isotype
- IgG
- Top Product
- Discover our top product CDK3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CDK3 (Cyclin-Dependent Kinase 3 (CDK3))
- Alternative Name
- CDK3 (CDK3 Products)
- Synonyms
- 2310050O10Rik antibody, Cdk3 antibody, cyclin dependent kinase 3 antibody, cyclin-dependent kinase 3 antibody, cyclin-dependent kinase 3, pseudogene antibody, CDK3 antibody, cgd3_1510 antibody, Chro.30182 antibody, Cdk3-ps antibody
- Background
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Background: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
Aliases: Cdk 3 antibody, Cdk3 antibody, CDK3_HUMAN antibody, CDKN3 antibody, Cell division kinase 3 antibody, Cell division protein kinase 3 antibody, Cyclin dependent kinase 3 antibody, Cyclin-dependent kinase 3 antibody, OTTHUMP00000206828 antibody, p36 antibody
- UniProt
- Q00526
- Pathways
- Cell Division Cycle
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