CNGA4 antibody (AA 1-575)

Catalog No. ABIN7148826

Product Details anti-CNGA4 Antibody

Target: CNGA4 (Cyclic Nucleotide Gated Channel alpha 4 (CNGA4))

Binding Specificity: AA 1-575

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNGA4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cyclic nucleotide-gated cation channel alpha-4 protein (1-575AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CNGA4

Target: CNGA4 (Cyclic Nucleotide Gated Channel alpha 4 (CNGA4))

Alternative Name: CNGA4 (CNGA4 Products)

Synonyms: CNCA2 antibody, CNG-4 antibody, CNG4 antibody, CNG5 antibody, CNGB2 antibody, OCNC2 antibody, OCNCBETA antibody, OCNCb antibody, Cgn2 antibody, rOCNC2 antibody, cyclic nucleotide gated channel alpha 4 antibody, CNGA4 antibody, Cnga4 antibody

Background:

Background: Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.

Aliases: CNGA4Cyclic nucleotide-gated cation channel alpha-4 antibody, Cyclic nucleotide-gated channel alpha-4 antibody, CNG channel alpha-4 antibody, CNG-4 antibody, CNG4 antibody

UniProt: Q8IV77