CXXC5 antibody (AA 1-227)

Catalog No. ABIN7148784

Product Details anti-CXXC5 Antibody

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Binding Specificity: AA 1-227

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CXXC-type zinc finger protein 5 protein (1-227AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CXXC5

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Alternative Name: CXXC5 (CXXC5 Products)

Synonyms: 4930415K17Rik antibody, CF5 antibody, RINF antibody, WID antibody, CXXC finger 5 antibody, CXXC finger protein 5 antibody, Cxxc5 antibody, CXXC5 antibody

Background:

Background: May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4 % oxygen), as well as normoxia conditions (20 % oxygen) (PubMed:23303788). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (PubMed:23303788).

Aliases: CF5 antibody, CXXC finger 5 protein antibody, CXXC finger protein 5 antibody, CXXC-type zinc finger protein 5 antibody, CXXC5 antibody, CXXC5_HUMAN antibody, HSPC195 antibody, Putative MAPK-activating protein PM08 antibody, Putative NF-kappa-B-activating protein 102 antibody, retinoid-inducible nuclear factor antibody, RINF antibody, TCCCIA00297 antibody, WID antibody, WT1-induced Inhibitor of Dishevelled antibody

UniProt: Q7LFL8