CELF4 antibody (AA 120-236) (HRP)

Catalog No. ABIN7148742

Product Details anti-CELF4 Antibody (HRP)

Target: CELF4 (CUGBP, Elav-Like Family Member 4 (CELF4))

Binding Specificity: AA 120-236

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CELF4 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CUGBP Elav-like family member 4 protein (120-236AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CELF4

Target: CELF4 (CUGBP, Elav-Like Family Member 4 (CELF4))

Alternative Name: CELF4 (CELF4 Products)

Synonyms: brunol4 antibody, zgc:92761 antibody, brunol-4 antibody, BRUNOL-4 antibody, BRUNOL4 antibody, A230070D14Rik antibody, Brul4 antibody, Brunol4 antibody, C130060B05Rik antibody, CUGBP, Elav-like family member 4 antibody, CUGBP, Elav-like family member 4 L homeolog antibody, CUGBP Elav-like family member 4 antibody, celf4 antibody, celf4.L antibody, CELF4 antibody, Celf4 antibody, LOC100732038 antibody

Background:

Background: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.

Aliases: CELF4 antibody, BRUNOL4 antibody, CUGBP Elav-like family member 4 antibody, CELF-4 antibody, Bruno-like protein 4 antibody, CUG-BP- and ETR-3-like factor 4 antibody, RNA-binding protein BRUNOL-4 antibody

UniProt: Q9BZC1

Pathways: Ribonucleoprotein Complex Subunit Organization, Synaptic Membrane