Crossover junction endonuclease EME1 (EME1) (AA 1-583) antibody

Catalog No. ABIN7148691

Product Details

Target: Crossover junction endonuclease EME1 (EME1)

Binding Specificity: AA 1-583

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Crossover junction endonuclease EME1 protein (1-583AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details

Target: Crossover junction endonuclease EME1 (EME1)

Alternative Name: EME1 (EME1 Products)

Synonyms: 6820428D13 antibody, essential meiotic structure-specific endonuclease 1 antibody, Eme1 antibody

Background:

Background: Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5\'-end at the branch nick. Typical substrates include 3\'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

Aliases: 6820428D13 antibody, Crossover junction endonuclease EME1 antibody, EC 3.1.22.- antibody, EME1 antibody, Eme1 essential meiotic endonuclease 1 homolog 1 (S. pombe) antibody, EME1, S. pombe, homolog of, 1 antibody, EME1_HUMAN antibody, essential meiotic endonuclease 1 homolog 1 (S pombe) antibody, Essential Meiotic Endonuclease 1 Homolog 1 antibody, essential meiotic endonuclease 1 homolog 2 antibody, Essential meiotic endonuclease 1, S. pombe, homolog of, 1 antibody, FLJ31364 antibody, hMMS4 antibody, homolog of yeast EME1 endonuclease antibody, MGC106543 antibody, MMS4 antibody, MMS4 homolog antibody, MMS4L antibody

UniProt: Q96AY2