HSD11B2 antibody (AA 212-343)

Catalog No. ABIN7148616

Product Details anti-HSD11B2 Antibody

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Binding Specificity: AA 212-343

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD11B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Corticosteroid 11-beta-dehydrogenase isozyme 2 protein (212-343AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HSD11B2

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Alternative Name: HSD11B2 (HSD11B2 Products)

Synonyms: MGC81883 antibody, 11-HSD2 antibody, AME antibody, AME1 antibody, HSD11K antibody, HSD2 antibody, SDR9C3 antibody, 11HSD2 antibody, HSD11B2 antibody, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog antibody, hydroxysteroid 11-beta dehydrogenase 2 antibody, hsd11b2.L antibody, HSD11B2 antibody, Hsd11b2 antibody

Background:

Background: Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Aliases: 11 beta HSD2 antibody, 11 beta hydroxysteroid dehydrogenase type 2 antibody, 11 DH2 antibody, 11-beta-HSD2 antibody, 11-beta-hydroxysteroid dehydrogenase type 2 antibody, 11-DH2 antibody, AME antibody, AME1 antibody, Corticosteroid 11 beta dehydrogenase isozyme 2 antibody, Corticosteroid 11-beta-dehydrogenase isozyme 2 antibody, DHI2_HUMAN antibody, HSD11B2 antibody, HSD11K antibody, HSD2 antibody, Hydroxysteroid 11 beta dehydrogenase 2 antibody, Hydroxysteroid 11 beta dehydrogenase isoenzyme 2 antibody, NAD dependent 11 beta hydroxysteroid dehydrogenase antibody, NAD-dependent 11-beta-hydroxysteroid dehydrogenase antibody, SDR9C3 antibody, Short chain dehydrogenase/reductase family 9C, member 3 antibody

UniProt: P80365

Pathways: Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones