H2AFY2 antibody (AA 1-260) (Biotin)

Catalog No. ABIN7148563

Product Details anti-H2AFY2 Antibody (Biotin)

Target: H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))

Binding Specificity: AA 1-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFY2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Core histone macro-H2A.2 protein (1-260AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for H2AFY2

Target: H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))

Alternative Name: H2AFY2 (H2AFY2 Products)

Synonyms: macroH2A2 antibody, RGD1561371 antibody, MGC69037 antibody, MGC130768 antibody, macroh2a2 antibody, im:6898017 antibody, wu:fa14g05 antibody, zgc:114051 antibody, H2AFY2 antibody, H2A histone family member Y2 antibody, H2A histone family, member Y2 antibody, H2A histone family member Y2 L homeolog antibody, core histone macro-H2A.2 antibody, H2AFY2 antibody, H2afy2 antibody, h2afy2.L antibody, h2afy2 antibody, LOC100224559 antibody, LOC100343925 antibody, LOC100456998 antibody, LOC489024 antibody, LOC100738475 antibody

Background:

Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

Aliases: Core histone macro H2A2.2 antibody, Core histone macro-H2A.2 antibody, Core histone macroH2A2.2 antibody, H2A histone family member Y2 antibody, H2AFY2 antibody, H2AW_HUMAN antibody, Histone macroH2A2 antibody, Macro H2A.2 antibody, Macro H2A2 antibody, MacroH2A.2 antibody, MacroH2A2 antibody, mH2A2 antibody

UniProt: Q9P0M6