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COPS3 antibody (AA 194-423)

COPS3 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7148495
  • Target See all COPS3 Antibodies
    COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
    Binding Specificity
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 194-423
    Reactivity
    • 49
    • 21
    • 21
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 43
    • 5
    • 1
    Rabbit
    Clonality
    • 44
    • 5
    Polyclonal
    Conjugate
    • 28
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS3 antibody is un-conjugated
    Application
    • 27
    • 14
    • 13
    • 13
    • 13
    • 11
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Cross-Reactivity
    Human, Mouse
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human COP9 signalosome complex subunit 3 protein (194-423AA)
    Isotype
    IgG
    Top Product
    Discover our top product COPS3 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    COPS3 (COP9 Signalosome Complex Subunit 3 (COPS3))
    Alternative Name
    COPS3 (COPS3 Products)
    Background

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    Aliases: Constitutive photomorphogenic homolog subunit 3 antibody, COP 9 (constitutive photomorphogenic) subunit 3 antibody, COP 9 complex homolog subunit 3 antibody, COP 9 complex S3 antibody, COP 9 complex subunit 3 antibody, COP 9 constitutive photomorphogenic homolog subunit 3 antibody, COP 9 homolog antibody, COP 9 signalosome complex subunit 3 antibody, COP 9 signalosome subunit 3 antibody, COP 9 subunit 3 antibody, COP9 (constitutive photomorphogenic) subunit 3 antibody, COP9 complex homolog subunit 3 antibody, COP9 complex S3 antibody, COP9 complex subunit 3 antibody, COP9 constitutive photomorphogenic homolog subunit 3 antibody, COP9 homolog antibody, COP9 signalosome complex subunit 3 antibody, COP9 signalosome subunit 3 antibody, COP9 subunit 3 antibody, COPS 3 antibody, cops3 antibody, CSN 3 antibody, CSN3 antibody, CSN3_HUMAN antibody, JAB 1 containing signalosome subunit 3 antibody, JAB1 containing signalosome subunit 3 antibody, JAB1-containing signalosome subunit 3 antibody, SGN 3 antibody, SGN3 antibody, Signalosome subunit 3 antibody

    UniProt
    Q9UNS2
    Pathways
    Cell Division Cycle
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