Contactin 1 antibody (AA 686-866) (HRP)

Catalog No. ABIN7148473

Product Details anti-Contactin 1 Antibody (HRP)

Target: Contactin 1 (CNTN1)

Binding Specificity: AA 686-866

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Contactin 1 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Contactin-1 protein (686-866AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Contactin 1

Target: Contactin 1 (CNTN1)

Alternative Name: CNTN1 (CNTN1 Products)

Synonyms: F3 antibody, GP135 antibody, AW495098 antibody, CNTN antibody, F3cam antibody, F3/F11 antibody, cntn-A antibody, F11 antibody, CNTN1 antibody, cntn1 antibody, contactin 1 antibody, contactin 1 L homeolog antibody, contactin 1a antibody, CNTN1 antibody, Cntn1 antibody, cntn1.L antibody, cntn1a antibody

Background:

Background: Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity).

Aliases: CNTN 1 antibody, CNTN antibody, Cntn1 antibody, CNTN1_HUMAN antibody, Contactin-1 antibody, Contactin1 antibody, F3 antibody, F3cam antibody, Glycoprotein gp135 antibody, gp 135 antibody, GP135 antibody, MYPCN antibody, Neural cell surface protein F3 antibody

UniProt: Q12860