C4A antibody (AA 1027-1186) (Biotin)

Catalog No. ABIN7148362

Product Details anti-C4A Antibody (Biotin)

Target: C4A (C4a) (Complement Fragment C4a (C4a))

Binding Specificity: AA 1027-1186

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4A antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Complement C4-A protein (1027-1186AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C4A

Target: C4A (C4a) (Complement Fragment C4a (C4a))

Alternative Name: C4A (C4a Products)

Synonyms: C4 antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4S antibody, CO4 antibody, CPAMD2 antibody, RG antibody, Slp antibody, C4-1 antibody, C4b antibody, complement C4A (Rodgers blood group) antibody, complement component 4A (Rodgers blood group) antibody, C4A antibody, C4a antibody

Background:

Background: Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.

Aliases: Acidic C4 antibody, Acidic complement C4 antibody, Basic C4 antibody, Basic complement C4 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody, C4, Chido form antibody, C4, Rodgers from antibody, C4A anaphylatoxin antibody, C4A antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4B antibody, C4B_2 antibody, C4B1 antibody, C4B12 antibody, C4B2 antibody, C4B3 antibody, C4BD antibody, C4F antibody, C4S antibody, CH antibody, Chido form of C4 antibody, CO4 antibody, CO4A_HUMAN antibody, Complement C4 A antibody, Complement C4 B antibody, Complement C4 gamma chain antibody, complement C4-A antibody, complement C4-B antibody, complement C4-B-like antibody, complement C4B1a antibody, Complement component 4A (Rodgers blood group) antibody, Complement component 4A antibody, complement component 4B (Chido blood group) antibody, complement component 4B (Chido blood group), copy 2 antibody, Complement component 4B (Childo blood group) antibody, Complement component 4B antibody, Complement component 4F antibody, Complement component 4S antibody, CPAMD2 antibody, CPAMD3 antibody, RG antibody, Rodgers form of C4 antibody

UniProt: P0C0L4

Pathways: Complement System