COPE antibody (AA 2-308) (Biotin)

Catalog No. ABIN7148015

Product Details anti-COPE Antibody (Biotin)

Target: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Binding Specificity: AA 2-308

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPE antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Coatomer subunit epsilon protein (2-308AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for COPE

Target: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Alternative Name: COPE (COPE Products)

Synonyms: COPE antibody, DDBDRAFT_0189670 antibody, DDBDRAFT_0233799 antibody, DDB_0189670 antibody, DDB_0233799 antibody, DKFZp469K1716 antibody, MGC80063 antibody, MGC130714 antibody, epsilon-COP antibody, 1110005D17Rik antibody, Cope1 antibody, coatomer protein complex subunit epsilon antibody, coatomer protein complex epsilon subunit antibody, coatomer protein complex subunit epsilon S homeolog antibody, coatomer protein complex, subunit epsilon antibody, COPE antibody, copE antibody, cope.S antibody, cope antibody, Cope antibody

Background:

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Aliases: 1110005D17Rik antibody, Coatomer epsilon subunit antibody, Coatomer protein complex subunit epsilon antibody, Coatomer subunit epsilon antibody, COPE antibody, COPE_HUMAN antibody, Cope1 antibody, Epsilon coat protein antibody, Epsilon COP antibody, Epsilon COP I antibody, Epsilon subunit of coatomer protein complex antibody, Epsilon-coat protein antibody, Epsilon-COP antibody, FLJ13241 antibody

UniProt: O14579