COPB2 antibody (AA 657-906)

Catalog No. ABIN7148013

Product Details anti-COPB2 Antibody

Target: COPB2 (Coatomer Protein Complex, Subunit beta 2 (COPB2))

Binding Specificity: AA 657-906

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Coatomer subunit beta\\\' protein (657-906AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for COPB2

Target: COPB2 (Coatomer Protein Complex, Subunit beta 2 (COPB2))

Alternative Name: COPB2 (COPB2 Products)

Background:

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).

Aliases: Beta'-coat protein antibody, Beta'-COP antibody, Coatomer subunit beta' antibody, Copb2 antibody, COPB2_HUMAN antibody, p102 antibody

UniProt: P35606