CBX2 antibody (AA 1-211) (Biotin)

Catalog No. ABIN7147698

Product Details anti-CBX2 Antibody (Biotin)

Target: CBX2 (Chromobox Homolog 2 (CBX2))

Binding Specificity: AA 1-211

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Chromobox protein homolog 2 protein (1-211AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CBX2

Target: CBX2 (Chromobox Homolog 2 (CBX2))

Alternative Name: CBX2 (CBX2 Products)

Synonyms: cbx2 antibody, M33 antibody, pc1 antibody, wu:fd20e09 antibody, zgc:103563 antibody, MOD2 antibody, pc antibody, CDCA6 antibody, SRXY5 antibody, cdca6 antibody, m33 antibody, chromobox 2 antibody, chromobox homolog 2 (Drosophila Pc class) antibody, chromobox 2 L homeolog antibody, cbx2 antibody, CBX2 antibody, Cbx2 antibody, cbx2.L antibody

Background:

Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \'Lys-119\', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.

Aliases: Cbx 2 antibody, CBX2 antibody, CBX2_HUMAN antibody, CDC A6 antibody, CDCA6 antibody, Cell division cycle associated 6 antibody, Cell division cycle associated6 antibody, chromobox homolog 2 (Pc class homolog, Drosophila) antibody, Chromobox homolog 2 antibody, Chromobox homolog2 antibody, Chromobox protein homolog 2 antibody, hromobox homolog 2 antibody, M33 antibody, M33 polycomb like antibody, MOD 2 antibody, MOD2 antibody, Modifier 3 antibody, Modifier3 antibody, Pc class homolog antibody, Polycomb antibody, SRXY5 antibody

UniProt: Q14781