CHRDL1 antibody (AA 92-237) (Biotin)

Catalog No. ABIN7147654

Product Details anti-CHRDL1 Antibody (Biotin)

Target: CHRDL1 (Chordin-Like 1 (CHRDL1))

Binding Specificity: AA 92-237

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRDL1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Chordin-like protein 1 protein (92-237AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHRDL1

Target: CHRDL1 (Chordin-Like 1 (CHRDL1))

Alternative Name: CHRDL1 (CHRDL1 Products)

Synonyms: CHL antibody, NRLN1 antibody, VOPT antibody, dA141H5.1 antibody, CHL1 antibody, Nrln1 antibody, chl antibody, vopt antibody, nrln1 antibody, da141h5.1 antibody, Kjr antibody, Neurogenesin-1 antibody, Ng1 antibody, chordin like 1 antibody, chordin-like 1 antibody, CHRDL1 antibody, Chrdl1 antibody, chrdl1 antibody

Background:

Background: Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.

Aliases: CHL antibody, chordin like 1 antibody, Chordin-like protein 1 antibody, CHRDL1 antibody, CRDL1_HUMAN antibody, dA141H5.1 antibody, neuralin 1 antibody, Neuralin-1 antibody, Neurogenesin-1 antibody, NRLN1 antibody, Ventroptin antibody, VOPT antibody

UniProt: Q9BU40