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CHMP2A antibody (AA 1-222) (Biotin)

CHMP2A Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7147520
  • Target See all CHMP2A Antibodies
    CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
    Binding Specificity
    • 15
    • 6
    • 2
    • 2
    • 1
    AA 1-222
    Reactivity
    • 24
    • 21
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 37
    • 2
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHMP2A antibody is conjugated to Biotin
    Application
    • 31
    • 13
    • 13
    • 13
    • 8
    • 6
    • 3
    • 2
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Charged multivesicular body protein 2a protein (1-222AA)
    Isotype
    IgG
    Top Product
    Discover our top product CHMP2A Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
    Alternative Name
    CHMP2A (CHMP2A Products)
    Synonyms
    BC-2 antibody, BC2 antibody, CHMP2 antibody, VPS2 antibody, VPS2A antibody, 1500016L11Rik antibody, RGD1305050 antibody, bc-2 antibody, bc2 antibody, chmp2 antibody, vps2 antibody, vps2a antibody, fj10d05 antibody, wu:fi18h03 antibody, wu:fj10d05 antibody, zgc:55361 antibody, charged multivesicular body protein 2a antibody, charged multivesicular body protein 2A antibody, Charged multivesicular body protein 2a antibody, charged multivesicular body protein 2A L homeolog antibody, ATEG_06167 antibody, LOC5570080 antibody, EDI_289610 antibody, PTRG_09933 antibody, NAEGRDRAFT_39042 antibody, PITG_17335 antibody, Tsp_00033 antibody, LOC100284170 antibody, LOC100284688 antibody, chm2a antibody, chmp2a antibody, CHMP2A antibody, Chmp2a antibody, chmp2a.L antibody
    Background

    Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis (PubMed:21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.

    Aliases: BC 2 antibody, BC2 antibody, Charged multivesicular body protein 2a antibody, CHM2A_HUMAN antibody, CHMP2 antibody, CHMP2a antibody, Chromatin modifying protein 2a antibody, Chromatin-modifying protein 2a antibody, hVps2 1 antibody, hVps2-1 antibody, putative breast adenocarcinoma marker antibody, Putative breast adenocarcinoma marker BC-2 antibody, Putative breast adenocarcinoma marker BC2 antibody, Vacuolar protein sorting associated protein 2 1 antibody, Vacuolar protein sorting-associated protein 2-1 antibody, Vps2 1 antibody, VPS2 antibody, Vps2-1 antibody, VPS2A antibody

    UniProt
    O43633
    Pathways
    SARS-CoV-2 Protein Interactome
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