CLN5 antibody (AA 42-181)

Catalog No. ABIN7147493

Product Details anti-CLN5 Antibody

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Binding Specificity: AA 42-181

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLN5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ceroid-lipofuscinosis neuronal protein 5 protein (42-181AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CLN5

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Alternative Name: CLN5 (CLN5 Products)

Synonyms: NCL antibody, A730075N08Rik antibody, CLN5, intracellular trafficking protein antibody, ceroid-lipofuscinosis, neuronal 5 antibody, CLN5 antibody, Cln5 antibody

Background:

Background: Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).

Aliases: Ceroid lipofuscinosis neuronal 5 antibody, Ceroid-lipofuscinosis neuronal protein 5 antibody, CLN5 antibody, CLN5_HUMAN antibody, NCL antibody, Protein CLN5 antibody

UniProt: O75503