CCM2 antibody (AA 1-300)

Catalog No. ABIN7147492

Product Details anti-CCM2 Antibody

Target: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Binding Specificity: AA 1-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCM2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Cerebral cavernous malformations 2 protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CCM2

Target: CCM2 (Cerebral Cavernous Malformation 2 (CCM2))

Alternative Name: CCM2 (CCM2 Products)

Synonyms: C7orf22 antibody, OSM antibody, malcavernin antibody, CCM2 antibody, BC029157 antibody, TUF2 antibody, vtn antibody, zgc:110233 antibody, CCM2 scaffolding protein antibody, cerebral cavernous malformation 2 antibody, malcavernin antibody, CCM2 antibody, Ccm2 antibody, LOC100304744 antibody, ccm2 antibody

Background:

Background: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity).

Aliases: C7orf22 antibody, Ccm2 antibody, CCM2 gene antibody, CCM2_HUMAN antibody, Cerebral cavernous malformation 2 antibody, Cerebral cavernous malformations 2 protein antibody, Chromosome 7 open reading frame 22 antibody, Malcavernin antibody, MGC4067 antibody, MGC4607 antibody, MGC74868 antibody, OSM antibody, Osmosensing scaffold for MEKK3 antibody, OTTHUMP00000159554 antibody, OTTHUMP00000214270 antibody, OTTHUMP00000214271 antibody, OTTHUMP00000214273 antibody, PP10187 antibody

UniProt: Q9BSQ5

Pathways: Cell-Cell Junction Organization