CEP63 antibody (AA 1-495) (HRP)

Catalog No. ABIN7147414

Product Details anti-CEP63 Antibody (HRP)

Target: CEP63 (Centrosomal Protein 63kDa (CEP63))

Binding Specificity: AA 1-495

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP63 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Centrosomal protein of 63 kDa protein (1-495AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CEP63

Target: CEP63 (Centrosomal Protein 63kDa (CEP63))

Alternative Name: CEP63 (CEP63 Products)

Background:

Background: Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes, this leads to the inactivation of spindle assembly and delay in mitotic progression.

Aliases: CEP63Centrosomal protein of 63 kDa antibody, Cep63 antibody

UniProt: Q96MT8

Pathways: M Phase