CEP63 antibody (AA 1-495)

Catalog No. ABIN7147411

Product Details anti-CEP63 Antibody

Target: CEP63 (Centrosomal Protein 63kDa (CEP63))

Binding Specificity: AA 1-495

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP63 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Centrosomal protein of 63 kDa protein (1-495AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CEP63

Target: CEP63 (Centrosomal Protein 63kDa (CEP63))

Alternative Name: CEP63 (CEP63 Products)

Synonyms: 4921501M07 antibody, AL450317.13gm1 antibody, AW107703 antibody, CD20R antibody, D9Mgc41 antibody, D9Mgc48e antibody, ET2 antibody, zgc:63548 antibody, Cep63-A antibody, Cep63-B antibody, Xcep63 antibody, centrosomal protein 63 antibody, centrosomal protein 63kDa antibody, centrosomal protein 63kDa L homeolog antibody, CEP63 antibody, SYO3AOP1_1060 antibody, Cep63 antibody, cep63 antibody, cep63.L antibody

Background:

Background: Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication, through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes, this leads to the inactivation of spindle assembly and delay in mitotic progression.

Aliases: CEP63Centrosomal protein of 63 kDa antibody, Cep63 antibody

UniProt: Q96MT8

Pathways: M Phase