CENPJ antibody (AA 1082-1248) (HRP)

Catalog No. ABIN7147365

Product Details anti-CENPJ Antibody (HRP)

Target: CENPJ (Centromere Protein J (CENPJ))

Binding Specificity: AA 1082-1248

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPJ antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Centromere protein J protein (1082-1248AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CENPJ

Target: CENPJ (Centromere Protein J (CENPJ))

Alternative Name: CENPJ (CENPJ Products)

Synonyms: CENPJ antibody, fi46g11 antibody, wu:fi46g11 antibody, si:dkey-46k9.9 antibody, BM032 antibody, CENP-J antibody, CPAP antibody, LAP antibody, LIP1 antibody, MCPH6 antibody, SASS4 antibody, SCKL4 antibody, Sas-4 antibody, 4932437H03Rik antibody, Gm81 antibody, centromere protein J antibody, Cenpj antibody, CENPJ antibody, cenpj antibody

Background:

Background: Plays an important role in cell division and centrosome function by participating in centriole duplication (PubMed:17681131, PubMed:20531387). Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles (PubMed:15047868, PubMed:27219064, PubMed:27306797). Required for centriole elongation and for STIL-mediated centriole amplification (PubMed:22020124). May be involved in the control of centriolar-microtubule growth by acting as a regulator of tubulin release (PubMed:27306797).

Aliases: BM032 antibody, CENP-J antibody, CENPJ antibody, CENPJ_HUMAN antibody, Centromere protein J antibody, Centrosomal P4.1-associated protein antibody, CPAP antibody, LAG-3-associated protein antibody, LAP antibody, LIP1 antibody, LYST interacting protein LIP1 antibody, LYST interacting protein LIP7 antibody, LYST-interacting protein 1 antibody, MCPH6 antibody, Sas 4 antibody, SASS4 antibody, SCKL4 antibody

UniProt: Q9HC77

Pathways: M Phase