TMEM2 antibody (AA 734-866)

Catalog No. ABIN7147330

Product Details anti-TMEM2 Antibody

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Binding Specificity: AA 734-866

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cell surface hyaluronidase protein (734-866AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TMEM2

Target: TMEM2 (Transmembrane Protein 2 (TMEM2))

Alternative Name: TMEM2 (TMEM2 Products)

Synonyms: 3110012M15Rik antibody, mKIAA1412 antibody, transmembrane protein 2 antibody, tmem2 antibody, TMEM2 antibody, Tmem2 antibody

Background:

Background: Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan, not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172).

Aliases: KIAA1412 antibody, TMEM 2 antibody, tmem2 antibody, TMEM2_HUMAN antibody, Transmembrane protein 2 antibody

UniProt: Q9UHN6