CISD2 antibody (AA 61-135) (Biotin)

Catalog No. ABIN7147223

Product Details anti-CISD2 Antibody (Biotin)

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Binding Specificity: AA 61-135

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CISD2 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CDGSH iron-sulfur domain-containing protein 2 protein (61-135AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CISD2

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Alternative Name: CISD2 (CISD2 Products)

Synonyms: ERIS antibody, Miner1 antibody, NAF-1 antibody, WFS2 antibody, ZCD2 antibody, 1500009M05Rik antibody, 1500026J14Rik antibody, 1500031D15Rik antibody, AI848398 antibody, B630006A20Rik antibody, Noxp70 antibody, Zcd2 antibody, RGD1566242 antibody, zgc:64148 antibody, eris antibody, miner1 antibody, wfs2 antibody, zcd2 antibody, cisd2 antibody, BcDNA:RE49709 antibody, Dmel\\CG1458 antibody, CDGSH iron sulfur domain 2 antibody, CDGSH iron sulfur domain 2 L homeolog antibody, CDGSH iron sulfur domain 2 S homeolog antibody, CISD2 antibody, Cisd2 antibody, cisd2 antibody, cisd2.L antibody, cisd2.S antibody

Background:

Background: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

Aliases: 1500009M05Rik antibody, 1500026J14Rik antibody, 1500031D15Rik antibody, AI848398 antibody, B630006A20Rik antibody, CDGSH iron sulfur domain 2 antibody, CDGSH iron-sulfur domain-containing protein 2 antibody, CDGSH type domain 2 antibody, CISD2 antibody, CISD2_HUMAN antibody, Endoplasmic reticulum intermembrane small protein antibody, ERIS antibody, Miner1 antibody, MitoNEET related 1 antibody, MitoNEET-related 1 protein antibody, NAF-1 antibody, Noxp70 antibody, Nutrient deprivation autophagy factor 1 antibody, Nutrient-deprivation autophagy factor-1 antibody, OTTHUMP00000219576 antibody, RGD1566242 antibody, WFS2 antibody, Zcd2 antibody, Zinc finger antibody, Zinc finger, CDGSH type domain 2 antibody

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response