ITGB1 antibody (AA 297-380)

Catalog No. ABIN7147139

Product Details anti-ITGB1 Antibody

Target: ITGB1 (Integrin beta 1 (ITGB1))

Binding Specificity: AA 297-380

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CD209 antigen protein (297-380AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: CD29 (ITGB1 Products)

Synonyms: CD29 antibody, FNRB antibody, GPIIA antibody, MDF2 antibody, MSK12 antibody, VLA-BETA antibody, VLAB antibody, 4633401G24Rik antibody, AA409975 antibody, AA960159 antibody, ENSMUSG00000051907 antibody, Fnrb antibody, Gm9863 antibody, gpIIa antibody, cd29 antibody, fnrb antibody, gpiia antibody, itgb1 antibody, mdf2 antibody, msk12 antibody, vla-beta antibody, vlab antibody, itgb1-a antibody, itgb1-b antibody, integrin subunit beta 1 antibody, integrin beta 1 (fibronectin receptor beta) antibody, integrin subunit beta 1 S homeolog antibody, integrin beta 1 antibody, integrin subunit beta 1 L homeolog antibody, ITGB1 antibody, Itgb1 antibody, itgb1.S antibody, LOC100009173 antibody, itgb1.L antibody

Background:

Background: Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.

Aliases: C type lectin domain family 4 member L antibody, C-type lectin domain family 4 member L antibody, CD 209 antibody, CD209 antibody, CD209 antigen antibody, CD209 antigen-like protein A antibody, CD209 Molecule antibody, CD209_HUMAN antibody, Cd209a antibody, CDSIGN antibody, CIRE antibody, CLEC4L antibody, DC SIGN antibody, DC SIGN1 antibody, DC-SIGN antibody, DC-SIGN1 antibody, DCSIGN antibody, Dendritic cell specific ICAM 3 grabbing nonintegrin 1 antibody, Dendritic cell specific ICAM3 grabbing nonintegrin 1 antibody, Dendritic cell-specific ICAM-3-grabbing non-integrin 1 antibody, Dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin antibody, Dengue fever, protection against, included antibody, Dentritic Cell Specific ICAM3 Grabbing Nonintegrin antibody, HIV GP120 Binding Protein antibody, MGC129965 antibody, MGC130443 antibody, SIGN-R1 antibody, SIGNR5 antibody

UniProt: Q9NNX6

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome