RQCD1 antibody (AA 1-258)

Catalog No. ABIN7147106

Product Details anti-RQCD1 Antibody

Target: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Binding Specificity: AA 1-258

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RQCD1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human CCR4-NOT transcription complex subunit 9 protein (1-258AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RQCD1

Target: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Alternative Name: CNOT9 (RQCD1 Products)

Synonyms: 2610007F23Rik antibody, AI593551 antibody, Fl10 antibody, CNOT9 antibody, CT129 antibody, RCD-1 antibody, RCD1 antibody, wu:fb52b11 antibody, wu:fb74e08 antibody, zgc:85618 antibody, CCR4-NOT transcription complex, subunit 9 antibody, CCR4-NOT transcription complex subunit 9 antibody, Cnot9 antibody, CNOT9 antibody, cnot9 antibody

Background:

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.

Aliases: CNOT9 antibody, RCD1 antibody, RQCD1CCR4-NOT transcription complex subunit 9 antibody, Cell differentiation protein RQCD1 homolog antibody, Rcd-1 antibody

UniProt: Q92600

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling