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CATSPER4 antibody (AA 306-472) (Biotin)

CATSPER4 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7147036
  • Target See all CATSPER4 Antibodies
    CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
    Binding Specificity
    • 15
    • 4
    • 1
    • 1
    AA 306-472
    Reactivity
    • 25
    • 1
    • 1
    Human
    Host
    • 26
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CATSPER4 antibody is conjugated to Biotin
    Application
    • 16
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)
    Isotype
    IgG
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
    Alternative Name
    CATSPER4 (CATSPER4 Products)
    Synonyms
    RGD1565213 antibody, 4933412L05 antibody, cation channel, sperm associated 4 antibody, cation channel sperm associated 4 antibody, Catsper4 antibody, CATSPER4 antibody
    Background

    Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .

    Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody

    UniProt
    Q7RTX7
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