Caspase 9 antibody (AA 113-324)
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- Target See all Caspase 9 (CASP9) Antibodies
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Binding Specificity
- AA 113-324
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 9 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Caspase-9 protein (113-324AA)
- Isotype
- IgG
- Top Product
- Discover our top product CASP9 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- Alternative Name
- CASP9 (CASP9 Products)
- Background
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Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Aliases: APAF-3 antibody, Apoptotic protease Mch-6 antibody, Apoptotic protease-activating factor 3 antibody, CASP-9 antibody, CASP9 antibody, CASP9_HUMAN antibody, Caspase 9 antibody, Caspase-9 subunit p10 antibody, ICE-LAP6 antibody, ICE-like apoptotic protease 6 antibody
- UniProt
- P55211
- Pathways
- MAPK Signaling, RTK Signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
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