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FLIP antibody (AA 1-250)

CFLAR Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7146901
  • Target See all FLIP (CFLAR) Antibodies
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Binding Specificity
    • 16
    • 15
    • 15
    • 9
    • 7
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-250
    Reactivity
    • 100
    • 67
    • 58
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 90
    • 14
    • 2
    Rabbit
    Clonality
    • 92
    • 14
    Polyclonal
    Conjugate
    • 52
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLIP antibody is un-conjugated
    Application
    • 95
    • 39
    • 26
    • 25
    • 20
    • 19
    • 12
    • 12
    • 11
    • 10
    • 9
    • 5
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human CASP8 and FADD-like apoptosis regulator protein (1-250AA)
    Isotype
    IgG
    Top Product
    Discover our top product CFLAR Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Alternative Name
    CFLAR (CFLAR Products)
    Synonyms
    Clarp1 antibody, cflar antibody, CFLAR antibody, FLIP antibody, CASH antibody, CASP8AP1 antibody, CLARP antibody, Casper antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, I-FLICE antibody, MRIT antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, 2310024N18Rik antibody, A430105C05Rik antibody, Cash antibody, ENSMUSG00000072980 antibody, Flip antibody, Gm9845 antibody, c-Flip antibody, CASP8 and FADD-like apoptosis regulator a antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator S homeolog antibody, CASP8 and FADD-like apoptosis regulator antibody, cflara antibody, CFLAR antibody, cflar antibody, cflar.S antibody, Cflar antibody
    Background

    Background: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.

    Aliases: c FLIP antibody, c FLIPL antibody, c FLIPR antibody, c FLIPS antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, CASH antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD-like apoptosis regulator subunit p12 antibody, CASP8AP1 antibody, Caspase homolog antibody, Caspase like apoptosis regulatory protein antibody, Caspase related inducer of apoptosis antibody, Caspase-eight-related protein antibody, Caspase-like apoptosis regulatory protein antibody, Casper antibody, cellular flice inhibitory protein antibody, Cellular FLICE-like inhibitory protein antibody, CFLA antibody, Cflar antibody, CFLAR_HUMAN antibody, CLARP antibody, FADD like anti apoptotic molecule antibody, FADD-like antiapoptotic molecule 1 antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, FLIP antibody, I FLICE antibody, I-FLICE antibody, Inhibitor of FLICE antibody, MACH-related inducer of toxicity antibody, MRIT antibody, OTTHUMP00000163715 antibody, OTTHUMP00000206475 antibody, OTTHUMP00000206476 antibody, OTTHUMP00000206478 antibody, OTTHUMP00000206479 antibody, OTTHUMP00000206480 antibody, OTTHUMP00000206482 antibody, OTTHUMP00000207360 antibody, Usurpin antibody, Usurpin beta antibody

    UniProt
    O15519
    Pathways
    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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