CMTR2 antibody (AA 301-600)

Catalog No. ABIN7146656

Product Details anti-CMTR2 Antibody

Target: CMTR2 (Cap Methyltransferase 2 (CMTR2))

Binding Specificity: AA 301-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMTR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cap-specific mRNA (nucleoside-2\'-O-)-methyltransferase 2 protein (301-600AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CMTR2

Target: CMTR2 (Cap Methyltransferase 2 (CMTR2))

Alternative Name: CMTR2 (CMTR2 Products)

Synonyms: AFT antibody, FTSJD1 antibody, MTr2 antibody, cap methyltransferase 2 antibody, CMTR2 antibody

Background:

Background: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2\'-O-ribose methylation to the 5\'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.

Aliases: CMTR2 antibody, AFT antibody, FTSJD1Cap-specific mRNA antibody, nucleoside-2'-O-)-methyltransferase 2 antibody, EC 2.1.1.296 antibody, Cap methyltransferase 2 antibody, Cap2 2'O-ribose methyltransferase 2 antibody, HMTr2 antibody, MTr2 antibody, FtsJ methyltransferase domain-containing protein 1 antibody, Protein adrift homolog antibody

UniProt: Q8IYT2