Calsequestrin antibody (AA 127-396)

Catalog No. ABIN7146581

Product Details anti-Calsequestrin Antibody

Target: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Binding Specificity: AA 127-396

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calsequestrin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Calsequestrin-1 protein (127-396AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Calsequestrin

Target: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Alternative Name: CASQ1 (CASQ1 Products)

Synonyms: CASQ antibody, PDIB1 antibody, casq1 antibody, CSQ antibody, CSQ-1 antibody, CSQ1 antibody, sCSQ antibody, zgc:154027 antibody, asph antibody, casq antibody, casq1.L antibody, pdib1 antibody, bZ1G18.2 antibody, zgc:100957 antibody, calsequestrin 1 antibody, Calsequestrin-1 antibody, calsequestrin 1b antibody, calsequestrin 1 S homeolog antibody, calsequestrin 1a antibody, CASQ1 antibody, casq1 antibody, Casq1 antibody, casq1b antibody, casq1.S antibody, casq1a antibody

Background:

Background: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1, this plays an important role in triggering muscle contraction.

Aliases: Calmitin antibody, Calmitine antibody, Calsequestrin 1 (fast twitch, skeletal muscle) antibody, Calsequestrin antibody, Calsequestrin, cell antibody, Calsequestrin, skeletal muscle isoform antibody, Calsequestrin-1 antibody, CASQ antibody, Casq1 antibody, CASQ1_HUMAN antibody, PDIB1 antibody, skeletal muscle isoform antibody

UniProt: P31415