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EFHA1 antibody (AA 26-247) (FITC)

EFHA1 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7146328
  • Target See all EFHA1 Antibodies
    EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))
    Binding Specificity
    • 4
    • 2
    • 1
    AA 26-247
    Reactivity
    • 24
    • 17
    • 17
    Human
    Host
    • 22
    • 2
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EFHA1 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Calcium uptake protein 2, mitochondrial protein (26-247AA)
    Isotype
    IgG
    Top Product
    Discover our top product EFHA1 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EFHA1 (EF-Hand Domain Family, Member A1 (EFHA1))
    Alternative Name
    MICU2 (EFHA1 Products)
    Synonyms
    1110008L20Rik antibody, EFHA1 antibody, Efha1 antibody, RGD1309934 antibody, Smhs2 antibody, 4833427E09Rik antibody, AU041871 antibody, mitochondrial calcium uptake 2 antibody, MICU2 antibody, Micu2 antibody
    Background

    Background: Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927).

    Aliases: 1110008L20Rik antibody, EF hand domain containing family member A1 antibody, EF hand domain family A1 antibody, EF hand domain family member A1 antibody, EF-hand domain-containing family member A1 antibody, EFHA1 antibody, EFHA1 EF hand domain family member A1 antibody, EFHA1_HUMAN antibody, FLJ25016 antibody, FLJ34588 antibody, Smhs2 homolog antibody

    UniProt
    Q8IYU8
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