Tescalcin antibody (AA 2-214) (Biotin)

Catalog No. ABIN7146266

Product Details anti-Tescalcin Antibody (Biotin)

Target: Tescalcin (TESC)

Binding Specificity: AA 2-214

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tescalcin antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Calcineurin B homologous protein 3 protein (2-214AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Tescalcin

Target: Tescalcin (TESC)

Alternative Name: TESC (TESC Products)

Synonyms: TSC antibody, chp3 antibody, CHP3 antibody, 1010001A17Rik antibody, 2410011K10Rik antibody, TE-1 antibody, RGD1566317 antibody, tescalcin antibody, tescalcin L homeolog antibody, tesc antibody, TESC antibody, Tesc antibody, tesc.L antibody

Background:

Background: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.

Aliases: TESC antibody, CHP3Calcineurin B homologous protein 3 antibody, Tescalcin antibody, TSC antibody

UniProt: Q96BS2

Pathways: Proton Transport