C4BPB antibody (AA 18-252)

Catalog No. ABIN7146168

Product Details anti-C4BPB Antibody

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Binding Specificity: AA 18-252

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4BPB antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human C4b-binding protein beta chain protein (18-252AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C4BPB

Target: C4BPB (Complement Component 4 Binding Protein, beta (C4BPB))

Alternative Name: C4BPB (C4BPB Products)

Synonyms: C4BPB antibody, C4BP antibody, C4bp-ps1 antibody, complement component 4 binding protein beta antibody, complement component 4 binding protein, beta antibody, C4BPB antibody, C4bpb antibody

Background:

Background: Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.

Aliases: C4b binding protein beta chain antibody, C4b-binding protein beta chain antibody, C4BP antibody, C4BPB antibody, C4BPB_HUMAN antibody, Complement component 4 binding protein beta antibody, Complement component 4 binding protein beta chain antibody, Complement component 4-binding protein beta antibody, OTTHUMP00000034288 antibody, OTTHUMP00000034289 antibody, OTTHUMP00000034375 antibody, OTTHUMP0000003474 antibody, Proline rich protein antibody, PRP antibody

UniProt: P20851

Pathways: Complement System