MRC2 antibody (AA 120-300)
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- Target See all MRC2 Antibodies
- MRC2 (Mannose Receptor, C Type 2 (MRC2))
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Binding Specificity
- AA 120-300
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MRC2 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Antigen Affinity Purified
- Immunogen
- Recombinant Human C-type mannose receptor 2 protein (120-300AA)
- Isotype
- IgG
- Top Product
- Discover our top product MRC2 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MRC2 (Mannose Receptor, C Type 2 (MRC2))
- Alternative Name
- MRC2 (MRC2 Products)
- Synonyms
- MRC2 antibody, cd280 antibody, uparap antibody, clec13e antibody, endo180 antibody, Endo180 antibody, CD280 antibody, CLEC13E antibody, ENDO180 antibody, UPARAP antibody, mKIAA0709 antibody, uPARAP antibody, mannose receptor C type 2 antibody, mannose receptor, C type 2 antibody, MRC2 antibody, mrc2 antibody, Mrc2 antibody
- Background
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Background: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Aliases: C-type lectin domain family 13 member E antibody, C-type mannose receptor 2 antibody, CD 280 antibody, CD280 antibody, CD280 antigen antibody, CLEC 13E antibody, CLEC13E antibody, ENDO 180 antibody, ENDO180 antibody, Endocytic receptor (macrophage mannose receptor family) antibody, Endocytic receptor 180 antibody, FLJ35911 antibody, KIAA0709 antibody, Macrophage mannose receptor 2 antibody, Mannose receptor C type 2 antibody, MRC 2 antibody, MRC2 antibody, MRC2_HUMAN antibody, UPAR-associated protein antibody, UPARAP antibody, Urokinase plasminogen activator receptor associated protein antibody, Urokinase receptor associated protein antibody, Urokinase receptor-associated protein antibody, Urokinase-type plasminogen activator receptor-associated protein antibody
- UniProt
- Q9UBG0
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