CLEC4E antibody (AA 41-219) (HRP)
-
- Target See all CLEC4E Antibodies
- CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
-
Binding Specificity
- AA 41-219
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CLEC4E antibody is conjugated to HRP
-
Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human C-type lectin domain family 4 member E protein (41-219AA)
- Isotype
- IgG
- Top Product
- Discover our top product CLEC4E Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
- Alternative Name
- CLEC4E (CLEC4E Products)
- Synonyms
- CLECSF9 antibody, MINCLE antibody, C86253 antibody, Clecsf9 antibody, Mincle antibody, CLEC4E antibody, C-type lectin domain family 4 member E antibody, C-type lectin domain family 4, member e antibody, C-type lectin domain family 4, member E antibody, CLEC4E antibody, Clec4e antibody, LOC611538 antibody
- Background
-
Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6\\\'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
Aliases: C type lectin domain family 4 member E antibody, C type lectin superfamily member 9 antibody, C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9 antibody, C-type lectin domain family 4 member E antibody, C-type lectin superfamily member 9 antibody, CLC4E_HUMAN antibody, CLEC 4E antibody, Clec4e antibody, CLECSF9 antibody, Macrophage inducible C type lectin antibody, Macrophage-inducible C-type lectin antibody, MINCLE antibody
- UniProt
- Q9ULY5
-