CCL5 antibody (AA 24-91)

Catalog No. ABIN7146006

Product Details anti-CCL5 Antibody

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Binding Specificity: AA 24-91

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human C-C motif chemokine 5 protein (24-91AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CCL5

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Alternative Name: CCL5 (CCL5 Products)

Synonyms: Rantes antibody, Scya5 antibody, D17S136E antibody, RANTES antibody, SCYA5 antibody, SIS-delta antibody, SISd antibody, TCP228 antibody, eoCP antibody, MuRantes antibody, C-C motif chemokine 5-like antibody, C-C motif chemokine ligand 5 antibody, chemokine (C-C motif) ligand 5 antibody, LOC100230935 antibody, CCL5 antibody, Ccl5 antibody

Background:

Background: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.

Aliases: Beta chemokine RANTES antibody, Beta chemokine RANTES precursor antibody, C C motif chemokine 5 antibody, CCL 5 antibody, CCL5 antibody, CCL5_HUMAN antibody, Chemokine (C C motif) ligand 5 antibody, Chemokine CC Motif Ligand 5 antibody, D17S136E antibody, EoCP antibody, Eosinophil chemotactic cytokine antibody, MGC17164 antibody, RANTES(4-68) antibody, Regulated upon activation normally T expressed and presumably secreted antibody, SCYA 5 antibody, SCYA5 antibody, SIS delta antibody, SIS-delta antibody, SISd antibody, Small inducible cytokine A5 (RANTES) antibody, Small inducible cytokine A5 antibody, Small inducible cytokine subfamily A (Cys Cys) member 5 antibody, Small-inducible cytokine A5 antibody, T cell specific protein p288 antibody, T cell specific protein RANTES antibody, T cell specific RANTES protein antibody, T cell-specific protein P228 antibody, T-cell-specific protein RANTES antibody, TCP 228 antibody, TCP228 antibody

UniProt: P13501

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration