CDCA8 antibody (AA 1-280)

Catalog No. ABIN7145712

Product Details anti-CDCA8 Antibody

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Binding Specificity: AA 1-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Borealin protein (1-280AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDCA8

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Alternative Name: CDCA8 (CDCA8 Products)

Background:

Background: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Aliases: BOR antibody, BOREA_HUMAN antibody, Borealin antibody, CDCA8 antibody, Cell division cycle associated 8 antibody, cell division cycle associated protein 8 antibody, Cell division cycle-associated protein 8 antibody, Dasra B antibody, Dasra-B antibody, DasraB antibody, FLJ10468 antibody, FLJ12042 antibody, hDasra B antibody, hDasra-B antibody, MESRGP antibody, OTTHUMP00000004514 antibody, pluripotent embryonic stem cell related gene 3 protein antibody, Pluripotent embryonic stem cell-related gene 3 protein antibody

UniProt: Q53HL2

Pathways: Cell Division Cycle, M Phase