BMP1 antibody (AA 317-424)

Catalog No. ABIN7145679

Product Details anti-BMP1 Antibody

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Binding Specificity: AA 317-424

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Bone morphogenetic protein 10 protein (317-424AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BMP1

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Alternative Name: BMP1 (BMP1 Products)

Synonyms: OI13 antibody, PCOLC antibody, PCP antibody, PCP2 antibody, TLD antibody, Pcp antibody, Tld antibody, BMP1 antibody, submp antibody, tld antibody, xtld antibody, bmp-1 antibody, pcolc antibody, xbmp1 antibody, tolloid antibody, BMP-1 antibody, bmp1 antibody, bmp1a antibody, bone morphogenetic protein 1 antibody, Bone morphogenetic protein 1 antibody, bone morphogenetic protein 1 S homeolog antibody, bone morphogenetic protein 1, like antibody, BMP1 antibody, Bmp1 antibody, bmp1 antibody, bmp1.S antibody, bmp1l antibody

Background:

Background: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Aliases: BMP-10 antibody, Bmp10 antibody, BMP10_HUMAN antibody, Bone morphogenetic protein 10 antibody, Bone morphogenetic protein 10 preproprotein antibody, MGC126783 antibody, OTTHUMP00000159973 antibody

UniProt: O95393

Pathways: Lipid Metabolism